Spanish Conquest of the Aztec Empire
Also called: Fall of Tenochtitlan
Spain’s Hernán Cortés, allied with Indigenous peoples hostile to the Aztecs, took the capital Tenochtitlan. The Aztec Empire fell and New Spain (Mexico) was founded.

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Landing on the Mexican coast from Cuba in 1519 with some 500 men, Cortés allied with Tlaxcala and others who resented Aztec rule, entered Tenochtitlan in November and took the emperor Moctezuma II hostage. When the city rose in June 1520 he fled with heavy losses (La Noche Triste), but returned with tens of thousands of Indigenous allies and besieged the lake city. With smallpox from Europe raging inside, Tenochtitlan fell on 13 August 1521. Mexico City was built on its ruins as the centre of the Viceroyalty of New Spain. Horses and steel, Indigenous allies and, above all, epidemic disease were the main causes of the conquest.