Science14 May 1796

Jenner’s Smallpox Vaccination

Also called: Smallpox vaccine, Vaccination, Cowpox

In 1796 the English physician Edward Jenner showed by experiment that inoculating people with cowpox could protect them from smallpox — the beginning of vaccines.

Edward Jenner vaccinating the boy James Phipps — painting by Eugène-Ernest Hillemacher, 1884
Edward Jenner vaccinating the boy James Phipps — painting by Eugène-Ernest Hillemacher, 1884

Eugène Ernest Hillemacher · CC BY 4.0 · Source

Smallpox was a terrible disease that killed about 30 per cent of those it struck. Early in the 18th century variolation — inoculation with matter from smallpox sores — reached Britain from the Ottoman Empire, but some of those inoculated fell ill and died. Jenner, a country doctor, took note of the saying that milkmaids who had caught the mild cowpox did not catch smallpox.

On 14 May 1796 Jenner inoculated eight-year-old James Phipps with matter from a milkmaid’s cowpox sores, and later confirmed that inoculation with smallpox matter no longer made him ill. When he published his results in 1798, vaccination spread rapidly around the world; the very word vaccine comes from the Latin vacca, “cow”. In 1980 the World Health Organization declared smallpox eradicated.

In Joseon, Jeong Yak-yong wrote the Magwa hoetong (1798) on measles and studied inoculation, and in 1879 Ji Seok-yeong learned cowpox vaccination at a Japanese naval hospital in Busan, first vaccinated people in Chungju and later published Udu sinseol.

The map in 1796

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States at the time
Great Britain

People

  • Edward Jenner1749 – 1823

    creator · English physician who developed vaccination, protecting people against smallpox by inoculating them with cowpox

Before and after

Earlier
1793 Macartney Embassy

Themes that include this event

  • Scientific Revolution, Enlightenment and the English Revolutions1543 – 1796

    The Scientific Revolution from Copernicus to Newton, parliamentary government in England won through the Puritan and Glorious Revolutions, and the Enlightenment that sought to remake society by reason — the groundwork of the civic revolutions and the Industrial Revolution